Human DNMT1 (Δexons3-5/Δexons3-5); DNMT3B (-/-) HCT116 Cell line is Double homozygous knockdown of DNMT1 exons 3-5 encoding PCNA binding domain and DNMT3B
Human DNMT1 (Δexons3-5/Δexons3-5); DNMT3B (-/-) HCT116 Cell line is Double homozygous knockout of DNMT1 exons 3-5 encoding PCNA binding domain and DNMT3B
Human DNMT1 (Δexons3-5/+); DNMT3B (-/-); CDKN2A (R24fs*20/-) HCT116 Cell line is Heterozygous knockdown of DNMT1 exons 3-5; homozygous knockdown of DNMT3B; heterozygous knockdown of wild type CDKN2A allele in heterozygous parental cells