HRE Luciferase Reporter-HeLa Cell Line

PVT21022

HRE-luciferase

17391 €

RC1018

HRE Luciferase Reporter-HeLa Cell Line

The HRE Luciferase Reporter cell line is a stably transfected HeLa cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the hypoxia response element (HRE). In response to hypoxia (low oxygen), HREs of target genes are recognized and regulated by the hypoxia-inducible factors (HIFs) which belong to the family of basic helix-loop-helix transcription factors and form heterodimeric complex comprising the alpha subunit (HIF-1 alpha, HIF-2 alpha and HIF-3 alpha) and beta subunit (Arnt1, Arnt2 and Arnt3), among which HIF-1 alpha and HIF-2 alpha are predominant isoforms. Activation of HIFs can also be mediated by chemical hydroxylase inhibitors as hypoxia mimetics including the iron chelator desferrioxamine and cobalt chloride.The HRE induction by cobalt chloride is shown in Figure 1.

2947.2 €

ABC-RC0095

Human HRE Reporter Cell Line–HeLa

Human HRE Reporter Cell Line is derived from HeLa cell. Gentaur can provide high quality reporter cell line for monitoring biological activity

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CBA-140

CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Fluorometric

958.72 €

CBA-140-5

CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Fluorometric

3616 €

CBA-325

StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible)

Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis.

1474.82 €