GATA3 Polyclonal Antibody
357.12 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 544 - MBS2561382-002mL
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 0.02mL
Parameters
| Storage and shipping | Store at -20 degree C. Avoid freeze/thaw cycles. |
|---|
5599-01mg
GATA3 Antibody
GATA3 Antibody: GATA3 is a zinc finger transcription factor that was first recognized as a possible determinant of T cell development. Later studies demonstrated that it is expressed in trophoblast giant cells and regulates trophoblast-specific genes during development. Specifically, GATA3 is selectively expressed in the trophectoderm of the peri-implantation embryo and regulates CDX2, which is required for the transcriptional repression of the POU5F1/Oct4 and NANOG genes and is thus essential for the segregation of the inner cell mass and trophectoderm at the blastocyst stage. Decreased or null-expression expression of GATA3 has also been suggested to play a major role in the development and progression of luminal breast cancer.
915.55 €
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