Desmethyl-QCA276
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On request
quantity
Produktdetaljer
Katalognummer: 931 - T18601-1g
Produktkategori: Företag och industri > Vetenskap och laboratorium
Leverantör:
Gentaur
Storlek: 1g
Parameters
| Additional information | SMILES: C(#CC=1SC2=C(C1CC=3C=CC=CC3)COCC4=NN=C(N42)C)C=5C=NNC5; Formula: C21H17N5OS |
|---|
HY-44103
Desmethyl-QCA276
Desmethyl-QCA276 (PROTAC BRD4-binding moiety 4), the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM[1]. Desmethyl-QCA276 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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