
Katalognummer: 1140 - 9000-10
Produktkategori: Företag och industri > Vetenskap och laboratorium
Storlek: 10 Plate
| Storage and shipping | Overnight |
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2593255
No wash sodium assay, 2 plates. Total assay solution for plate-based, high-throughput measurements of intracellular sodium flux. Also endpoint assay compatible.Excitation: 525 nm | Emission: 545 nmION’s Brilliant Sodium Assay is a total assay solution for multi-well plate-based, high-throughput measurements of changes in intracellular Na⁺ mediated through a wide-variety of plasma membrane and intracellular sodium channels and transporters. In multi-well, plate-based formats, the Brilliant Sodium Assay can be used to discover and characterize the effects of many tens-of-thousands of compounds and environmental factors on effectors of intracellular Na⁺. ION’s Brilliant Sodium Assay provides all the reagents necessary for use as a wash or no-wash assay with adherent or non-adherent cells. The optional use of a probenecid solution and an extracellular background masking solution (TRS) offers the ultimate in compatibility for cells types which are difficult to load with fluorescent Na⁺ indicators (e.g. Chinese Hamster Ovary, CHO cells) and when performing assays in complete, serum-containing cell culture medium is desired.ION’s Brilliant Sodium Assay is compatible with fluorescence microscopes, flow cytometers, and plate readers capable of detecting fluorescein or more optimally, yellow fluorescent protein (YFP).
9000-100
No wash sodium assay, 10 plates. Total assay solution for plate-based, high-throughput measurements of intracellular sodium flux. Also endpoint assay compatible.Excitation: 525 nm | Emission: 545 nmION’s Brilliant Sodium Assay is a total assay solution for multi-well plate-based, high-throughput measurements of changes in intracellular Na⁺ mediated through a wide-variety of plasma membrane and intracellular sodium channels and transporters. In multi-well, plate-based formats, the Brilliant Sodium Assay can be used to discover and characterize the effects of many tens-of-thousands of compounds and environmental factors on effectors of intracellular Na⁺. ION’s Brilliant Sodium Assay provides all the reagents necessary for use as a wash or no-wash assay with adherent or non-adherent cells. The optional use of a probenecid solution and an extracellular background masking solution (TRS) offers the ultimate in compatibility for cells types which are difficult to load with fluorescent Na⁺ indicators (e.g. Chinese Hamster Ovary, CHO cells) and when performing assays in complete, serum-containing cell culture medium is desired.ION’s Brilliant Sodium Assay is compatible with fluorescence microscopes, flow cytometers, and plate readers capable of detecting fluorescein or more optimally, yellow fluorescent protein (YFP).
11000-10
No wash thallium assay, 10 plates. Total assay solution for plate-based, high-throughput measurements of intracellular thallium flux. Also useful for potassium and sodium channels, cation transporters, and GPCRs. Excitation: 490 nm | Emission: 515 nmION Biosciences' Brilliant Thallium (Tl⁺) Assay is a total assay solution for multi-well plate-based, high-throughput measurements of Tl⁺ flux through K⁺, Na⁺, non-selective cation channels, and some Na⁺ or K⁺ transporters. The ION Biosciences' Brilliant Thallium Assay is also useful for a wide range of effectors of ion channels and transporters including G protein-coupled receptors, lipid and protein kinase, for example. In multi-well, plate-based formats, the Brilliant Thallium Assay can be used to discover and characterize the effects of tens to many tens-of-thousands of compounds and environmental factors on effectors of Tl⁺ flux. Over the past 15 years, fluorescence-based measures of Tl⁺ flux have been widely utilized to discover small molecule modulators of a host of ion channels, transporters, GPCRS and other targets of interest for both drug discovery and basic research.

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