Bmi-1 Rabbit Polyclonal Antibody(F270)
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On request
quantity
Produktdetaljer
Katalognummer: 772 - BT-AP14458-20ul
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 20ul
Parameters
| Additional information | WB |
|---|---|
| Storage and shipping | -20°C for 1 year |
BT-AP14458-100ul
Bmi-1 Rabbit Polyclonal Antibody(F270)
This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene.
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