Biotinylated Human TFPI Protein, His Tag, ultra sensitivity (primary amine labeling)

Biotinylated Human TFPI Protein, His Tag, ultra sensitivity (primary amine labeling)

580.32 EUR

580.32 EUR
In Stock
quantity
Produktdetaljer

Katalognummer: 716 - TFI-H8226

Produktkategori: Företag och industri > Vetenskap och laboratorium

Leverantör:

ACROBIOSYSTEMSGentaur

Storlek: 200ug

Parameters

Additional informationTissue factor pathway inhibitor (TFPI) is also known as Extrinsic pathway inhibitor (EPI), Lipoprotein - associated coagulation inhibitor (LACI), is a plasma proteinase inhibitor synthesized by vascular endothelial cells and part of it is associated with glycosaminoglycans of these cells. TFPI is a single-chain polypeptide which can reversibly inhibit Factor Xa (Xa) and Thrombin (Factor IIa). TFPI is a secreted protein with a N­terminal acidic region, three Kunitz (K) domains separated with by two linker regions, and a C­terminal basic region. The first K domain inhibits coagulation factor VIIa complexed to tissue factor (TF); The second K domain inhibits factor Xa; The third K domain binds to heparin; The C­terminal basic region may have several functions. For example, it plays an important role in binding of TFPI to cell surfaces.
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