Biotinylated Human LOXL2 Protein, His,Avitag™
1985.76 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 716 - LO2-H82E3
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 25ug
Parameters
| Additional information | Lysyl oxidase homolog 2 is also known as LOXL2, Lysyl oxidase-like protein 2, which is expressed in many tissues, highest expression in reproductive tissues, placenta, uterus and prostate, Up-regulated in a number of cancers cells and tissues. LOXL2 mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. LOXL2 acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. LOXL2 acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation. |
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| Storage and shipping | -20℃ RT |
LO2-H82E3
Biotinylated Human LOXL2 Protein, His,Avitag™
Biotinylated Human LOXL2, His,Avitag (LO2-H82E3) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Gln 774 (Accession # Q9Y4K0-1).
1985.76 €
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2215.32 €
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