Biotinylated Human G-CSF R / CD114 Protein, Avitag™,His Tag (MALS verified)
2215.32 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 716 - GCR-H82E4
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 25ug
Parameters
| Additional information | Granulocyte Colony Stimulating Factor Receptor (G-CSFR) is also known as Cluster of Differentiation 114 (CD114), CSF3R and GCSF, is a cell-surface receptor for the granulocyte colony-stimulating factor (G-CSF), a cytokine that plays a critical role in the regulation of the activation, proliferation, differentiation, and survival of the neutrophilic granulocyte lineage. G-CSFR belongs to a family of cytokine receptors known as the hematopoietin receptor family. This type I membrane protein has a composite structure consisting of an immunoglobulin(Ig)-like domain, a cytokine receptor-homologous (CRH) domain and three fibronectin type I II (FNIII) domains in the extracellular region. G-CSFR is present mainly on precursor cells in the bone marrow, and, in response to stimulation by G-CSF, initiates cell proliferation and differentiation into mature neutrophilic granulocytes and macrophages. G-CSFR mediates the specific effect of GCSF through activating a variety of intracellular signaling cascades, including the Jak/Stat, PI3/Akt, Ras-Raf-MAP kinase, and Src family kinase pathways, and thus functions in defense against infection, inflammation and repair, and in the maintenance of steady state hematopoiesis. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. Mutations in the intracellular part of this receptor are also associated with certain types of leukemia. |
|---|---|
| Storage and shipping | -20℃ RT |
GCR-H82E4
Biotinylated Human G-CSF R / CD114 Protein, Avitag™,His Tag (MALS verified)
Biotinylated Human G-CSF R, Avitag,His Tag (GCR-H82E4) is expressed from human 293 cells (HEK293). It contains AA Glu 25 - Pro 621 (Accession # NP_000751).
2215.32 €
EGR-H82F8
Biotinylated Human EGF R Protein, Fc,Avitag™ (MALS verified)
Biotinylated Human EGF R, Fc,Avitag (EGR-H82F8) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Ser 645 (Accession # P00533-1).
2215.32 €
EGR-H82E3
Biotinylated Human EGF R Protein, His,Avitag™ (MALS verified)
Biotinylated Human EGF R, His,Avitag (EGR-H82E3) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Ser 645 (Accession # P00533-1).
2215.32 €
DL3-H82E4
Biotinylated Human DLL3 Protein, His,Avitag™ (MALS verified)
Biotinylated Human DLL3, His,Avitag (DL3-H82E4) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Leu 492 (Accession # Q9NYJ7-1).
2215.32 €
CD4-H82E3
Biotinylated Human CD34 Protein, His,Avitag™ (MALS verified)
Biotinylated Human CD34 Protein, His,Avitag (CD4-H82E3) is expressed from human 293 cells (HEK293). It contains AA Ser 32 - Thr 290 (Accession # P28906-1).
2019.12 €
CD2-H82E3
Biotinylated Human CD72 Protein, His,Avitag™ (MALS verified)
Biotinylated Human CD72, His,Avitag (CD2-H82E3) is expressed from human 293 cells (HEK293). It contains AA Arg 117 - Asp 359 (Accession # P21854-1).
2215.32 €
Håll dig uppdaterad! Visa tidigare publikationer
By: Author , 2 Comment
Anaplasmos hos hundar och katter – allt du behöver veta
23 August 2025
By: Author , 2 Comment
Solbränna – hur leker man säkert i solen?
16 August 2025
By: Author , 2 Comment
Biologiska läkemedel – Modernitet inom farmaci
1 August 2025
By: Author , 2 Comment
Icke-steroida antiinflammatoriska läkemedel – viktig information om populära läkemedel
22 July 2025