AX-024 hydrochloride
0.01 EURAsk for quotation
0.01 EURAsk for quotation
On request
quantity
Produktdetaljer
Katalognummer: 931 - T4403-5mg
Produktkategori: Företag och industri > Vetenskap och laboratorium
Leverantör:
Gentaur
Storlek: 5mg
Parameters
| Additional information | SMILES: Cl.COc1ccc2OCC(CN3CCCC3)=C(c3ccc(F)cc3)c2c1; Formula: C21H23ClFNO2 |
|---|
HY-107390A
AX-024 (hydrochloride)
AX-024 hydrochloride is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ~1 nM. AX-024 hydrochloride modulates cell signaling by targeting SH3 domains. AX-024 hydrochloride has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-α, IFN-γ, IL-10 and IL-17A.
519.55 €
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