Arrestin-Beta-1 Monoclonal Antibody

Arrestin-Beta-1 Monoclonal Antibody

366 EUR

366 EUR
In Stock
quantity
Produktdetaljer

Katalognummer: 965 - JOT-MCA0185-50ul

Produktkategori: Företag och industri > Vetenskap och laboratorium

Leverantör:

JotbodyGentaur

Storlek: 50ul

Parameters

Additional informationMembers of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.