APC Anti-Human/Mouse/Rat CD47 Antibody[MIAP410]

E16FMA047-025U

APC anti-mouse CD47

Available in various conjugation types.

865 €

E16FMA047-100U

APC anti-mouse CD47

Available in various conjugation types.

1774.99 €

DL20776F-20Tests

APC Anti-Human CD47 Antibody

CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47; in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.

517.5 €

MBS6268534-5x01mL

CD47 (APC)

5699.38 €

MBS6268535-01mL

CD47 (APC)

1402.62 €

MBS6268535-5x01mL

CD47 (APC)

5463.5 €