Anti-STAT5A antibody

MBS176110-01mg

Anti-STAT5a antibody

758.75 €

MBS176110-5x01mg

Anti-STAT5a antibody

2569.25 €

STJ113363

Anti-STAT5A antibody

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene.

648.6 €

MBS8103743-01mL

Anti-STAT5a Antibody, Rabbit Polyclonal

567.5 €

MBS8103743-5x01mL

Anti-STAT5a Antibody, Rabbit Polyclonal

1715 €

MBS8100620-01mL

Anti-STAT5a Antibody, Rabbit Polyclonal

567.5 €