Anti-Mouse CD22 Monoclonal Antibody (PE/Cyanine5 Conjugated) [Cy34.1]

STJ16100300

Anti-Mouse-CD34 antibody

765.6 €

DL20366F-20Tests

Anti-Mouse CD22 Monoclonal Antibody(PE Conjugated)

The Cy34.1 monoclonal antibody specifically binds to the B-lymphocyte differentiation antigen CD22 on strains having the Lyb-8.2 alloantigen (e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, SWR, but not AKR, DBA/1, DBA/2, NZB, PL). CD22 is expressed at high levels on mature peripheral B lymphocytes (follicular and marginal zone), B-1 cells (CD5+ B cells), and plasma cells. It is a member of the Ig gene superfamily and associates with the B-cell antigen receptor. Its sialic acid- binding immunoglobulin-like lectin (siglec) extracellular region mediates B-cell adhesion to ligands on endothelial cells in the bone marrow. Its intracellular domain is phosphorylated after cross-linking of antigen receptor or MHC class II antigen. It is involved in negative regulation of B-cell activation and protection from autoimmunity. B-cell proliferative responses to LPS or anti-mouse Ig µ chain are augmented in the presence of Cy34.1 mAb.

330 €

DL20366F-50Tests

Anti-Mouse CD22 Monoclonal Antibody(PE Conjugated)

The Cy34.1 monoclonal antibody specifically binds to the B-lymphocyte differentiation antigen CD22 on strains having the Lyb-8.2 alloantigen (e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, SWR, but not AKR, DBA/1, DBA/2, NZB, PL). CD22 is expressed at high levels on mature peripheral B lymphocytes (follicular and marginal zone), B-1 cells (CD5+ B cells), and plasma cells. It is a member of the Ig gene superfamily and associates with the B-cell antigen receptor. Its sialic acid- binding immunoglobulin-like lectin (siglec) extracellular region mediates B-cell adhesion to ligands on endothelial cells in the bone marrow. Its intracellular domain is phosphorylated after cross-linking of antigen receptor or MHC class II antigen. It is involved in negative regulation of B-cell activation and protection from autoimmunity. B-cell proliferative responses to LPS or anti-mouse Ig µ chain are augmented in the presence of Cy34.1 mAb.

442.5 €

MBS2558160-01mg

Anti-Mouse CD22 Monoclonal Antibody (PE/Cyanine5 Conjugated) [Cy34.1]

471.88 €

MBS2558160-5x01mg

Anti-Mouse CD22 Monoclonal Antibody (PE/Cyanine5 Conjugated) [Cy34.1]

1453.62 €

MBS2558161-0025mg

Anti-Mouse CD22 Monoclonal Antibody (PE/Cyanine7 Conjugated) [Cy34.1]

363.5 €