Anti-Human CD274 Therapeutic Antibody

TRI-AB-053

Anti-Human CD274 Therapeutic Antibody

2630 €

TRI-AB-015

Anti-Human CD28 Therapeutic Antibody

2630 €

TRI-AB-058

Anti-Human CD19 Therapeutic Antibody

2630 €

DL21670F-20Tests

PE/Cyanine7 Anti-Human CD274/PD-L1 Antibody

CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.

506.25 €

DL21670F-50Tests

PE/Cyanine7 Anti-Human CD274/PD-L1 Antibody

CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.

652.5 €

JOT21669F

PE/Cyanine5 Anti-Human CD274/PD-L1 Antibody

PE/Cyanine5

474.19 €