Anti-HMG2L1 polyclonal antibody
652.5 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 421 - 25290
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 100 µl
STJ96867
Anti-HMG-1 antibody
HMG-1 is a protein encoded by the HMGB1 gene which is approximately 24,8 kDa. HMG-1 is localised to the nucleus, cytoplasm and cell membrane. It is involved in activated TLR4 signalling, cytosolic sensors of pathogen-associated DNA,the innate immune system and apoptosis induced DNA fragmentation. It is a multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus, it is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodelling, DNA repair and genome stability. HMG-1 is ubiquitously expressed in human tissues. Mutations in the HMGB1 gene may result in endophthalmitis. STJ96867 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal Antibody detects endogenous levels of HMG-1 protein.
504.6 €
Håll dig uppdaterad! Visa tidigare publikationer
By: Author , 2 Comment
Anaplasmos hos hundar och katter – allt du behöver veta
23 August 2025
By: Author , 2 Comment
Solbränna – hur leker man säkert i solen?
16 August 2025
By: Author , 2 Comment
Biologiska läkemedel – Modernitet inom farmaci
1 August 2025
By: Author , 2 Comment
Icke-steroida antiinflammatoriska läkemedel – viktig information om populära läkemedel
22 July 2025