Anti-HER2/ErbB2 antibody

A00539

Anti-HER3 ERBB3 Antibody

Boster Bio Anti-HER3 ERBB3 Antibody (Catalog # A00539). Tested in ELISA, IP, WB applications. This antibody reacts with Human.

991.5 €

ER0106

Anti-HER2 / ErbB2 Antibody

HER2 is a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family. Amplification or overexpression of this oncogene has been shown to play an important role in the development and progression of certain aggressive types of breast cancer. In recent years the protein has become an important biomarker and target of therapy for approx. 30% of breast cancer patients. Over-expression is also known to occur in ovarian, stomach, and aggressive forms of uterine cancer, such as uterine serous endometrial carcinoma. The expression of HER2 is regulated by signaling through estrogen receptors. Normally, estradiol and tamoxifen acting through the estrogen receptor down-regulate the expression of HER2. However, when the ratio of the coactivator AIB-3 exceeds that of the corepressor PAX2, the expression of HER2 is upregulated in the presence of tamoxifen, leading to tamoxifen-resistant breast cancer.

433.5 €

MBS9231151-01mL

Anti-HER2/ErbB2 Antibody

726.88 €

MBS8112763-01mL

Anti-HER3/ERBB3 Antibody, Rabbit Polyclonal

567.5 €

MBS8112763-5x01mL

Anti-HER3/ERBB3 Antibody, Rabbit Polyclonal

1715 €

MBS8112764-01mL

Anti-HER3/ERBB3 Antibody, Rabbit Polyclonal

567.5 €