AIRE-1 Polyclonal Antibody

AIRE-1 Polyclonal Antibody

480 EUR

480 EUR
In Stock
quantity
Produktdetaljer

Katalognummer: 965 - JOT-AP00311-100ul

Produktkategori: Företag och industri > Vetenskap och laboratorium

Leverantör:

JotbodyGentaur

Storlek: 100ul

Parameters

Additional informationAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).