ABflo® 488 Rabbit anti-Human ERG mAb
649.5 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 806 - A22496
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 100μg
Parameters
| Additional information | This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces, for example, on monocytes. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. Platelets and monocytes have been shown to express this coagulation factor under procoagulatory and proinflammatory stimuli, and a major role in HIV-associated coagulopathy has been described. Platelet-dependent monocyte expression of coagulation factor III has been described to be associated with Coronavirus Disease 2019 (COVID-19) severity and mortality. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants. |
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| Storage and shipping | Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.03% proclin300,0.2% BSA,pH7.3. |
A22496
ABflo® 488 Rabbit anti-Human ERG mAb
Recombinant fusion protein containing a sequence corresponding to amino acids 34-251 of human CD142 (NP_001984.1).
649.5 €
A22497
ABflo® 647 Rabbit anti-Human ERG mAb
Recombinant fusion protein containing a sequence corresponding to amino acids 23-116 of cat CD3G (XP_003992456.3).
649.5 €
A22185
ABflo® 488 Rabbit anti-Human CD5 mAb
Recombinant fusion protein containing a sequence corresponding to amino acids 19-515 of human CD141/Thrombomodulin (NP_000352.1).
452.88 €
A22216
ABflo® 488 Rabbit anti-Human LAMP2 mAb
Recombinant fusion protein containing a sequence corresponding to amino acids 26-180 of human CD7 (NP_006128.1).
521.97 €
A22300
ABflo® 488 Rabbit anti-Human CD79a mAb
Recombinant fusion protein containing a sequence corresponding to amino acids 28-480 of human ICAM-1/CD54 (NP_000192.2).
739.83 €
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