5-FOA, 25g
1334.01 EUR
1334.01 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 542 - R7039
Produktkategori: Företag och industri > Vetenskap och laboratorium
Leverantör:
Gentaur
Storlek: 25g
Parameters
| Additional information | 5-FOA ((5-Fluoroorotic acid), Monohydrate)p/n and sizes: R7039-5g, R7039-25g, & BulkUsed as a research tool in molecular genetics. Yeast Selection Reagent. Employed in the selection of resistant strains of Saccharomyces cerevisiae that possess a mutant URA3 gene which renders them orotidine-5-phosphate decarboxylase deficient. 5-FOA is converted 5-fluorouridine monophosphate (5-FUMP) in yeast cells, which can become incorporated into RNA or metabolized to the highly toxic 5-fluoro-2-deoxyuridine monophosphate (5-FdUMP). 5-FdUMP is a potential inhibitor of thyidylate Sythase (TS), causing a cessation in DNA synthesis. For research use. Solubility: 50mg in 1ml (1:1) ammonium hydroxide-water with gentle heating.Purity: ≥98%Molecular Weight: 174.09Molecular Formula: C5H3FN2O4CAS: 703-95-7Storage: -20°C |
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