GWB-PS34F1

Wnt Signaling Pathway TCF/LEF reporter-HEK293 stable cell line

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60405

AP-1 Reporter - HEK293 Cell Line (JNK signaling pathway)

The AP-1 Reporter - HEK293 Cell Linee is designed for monitoring the activity of the JNK signaling pathway. The AP1 Reporter - HEK293 cell line contains a firefly luciferase gene under the control of AP1-responsive elements that are stably integrated into HEK293 cells.

3855.68 €

60652

Notch Signaling Pathway Notch1/CSL Reporter - HEK293 Cell Line

The Notch CSL Reporter - HEK293 cell line contains the firefly luciferase gene under the control of Notch-response elements (CSL responsive elements) alone with expression construct for Notch1 E (NOTCH1 that has a deletion of the entire extracellular domain) stably integrated into HEK293 cells. Inside the cells, the Notch1 E can be cleaved by γ-secretase. The active Notch1 NICD is released to nucleus and induces the constitutive expression of luciferase reporter. The cell line is validated for the inhibition of the expression of luciferase reporter using a known inhibitor of the Notch signaling pathway.

3446.63 €

60409

Gli Reporter - NIH3T3 Cell line (Hedgehog Pathway)

The Gli Reporter - NIH3T3 Cell Line is designed for monitoring the activity of the hedgehog signaling pathway. The Gli Reporter - NIH3T3 Cell Line contains the firefly luciferase gene under the control of Gli responsive elements stably integrated into NIH3T3 cells. Luciferase expression correlates with activation of the hedgehog signaling pathway.

3855.68 €

GWB-PS5E51

Nrf antioxidant pathway ARE reporter cell line

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GWB-PS8936

Gli Reporter - NIH3T3 Cell line (Hedgehog Pathway)

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