Catalog number: 10021 - T6980
Product Category: Business & Industrial > Science & Laboratory
Size: 1x10^6 cells / 1.0 ml
60545
Recombinant CHO-K1 cell transfected with empty expression vector containing the hygromycin resistance gene._x000D_This cell line serves as a negative control for:_x000D_ TCR Activator - CHO Recombinant Cell line, #60539; DAT CHOK1 Recombinant Cell Line, #60558; and NET - CHOK1 Recombinant Cell , #60557
60622
An NF-κB luciferase reporter construct is stably integrated into the genome of CHO-K1 cells. The firefly luciferase gene is controlled by the NF-κB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-κB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene._x000D_The NF-κB-luciferase / CHO-K1 cell line is suitable for monitoring the activity of NF-κB transcription factor through luminescence readout.). This cell line responds to human cytokine IL-1β, responds moderately to human TNF, and does not respond to human IFN-λ (2 µg/ml). Reducing the amount of serum during incubation period may increase the sensitivity to cytokines. Since CHO-K1 cells do not express endogenous human proteins, this cell line provides an excellent platform to enable exogenous expression of a protein of interest to study its downstream effect on NF-κB signaling.
78097-H
Recombinant human Nectin4-CHO K1 cell line stably expressing a full length human Nectin4/PVRL4 receptor (GenBank Accession: NM_030916.2). Surface expression of hNectin4 was confirmed by flow cytometry. Each stable clonal cell line was selected for different levels of hNectin4 expression (High, Medium, Low) to mimic different stages of cancer target cells with various Nectin4 expression levels.