Sheep Polyclonal anti-Human CTLA-4
757.50 €
757.50 €
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Catalog number: 535 - hAP-5812
Product Category: Business & Industrial > Science & Laboratory
Supplier:
Gentaur
Size: 50ug
101-M345
Anti-Human CTLA-4 Antibody
CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA-4 is up-regulated rapidly following T cell activation and CD28 ligation. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28.
755.99 €