Catalog number: 607 - P1037-.1
Product Category: Business & Industrial > Science & Laboratory
Size: 100ug
P1037-.05
Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor at the early stages of hematopoiesis. SCF promotes the survival, differentiation, and mobilization of myeloid, erythroid, megakaryocytic, lymphoid and melanocyte progenitors
PROTQ99P86-1
RELMβ (Resistin-like molecule β/FIZZ2) is an 18 kDa disulfide-linked homodimeric protein expressed in the epithelium of the colon and small bowel. The biological functions of RELMβ, and its molecular targets, are not fully known but, it has been suggested that it plays a regulatory role during inflammation and may also act to establish links among adipose tissue, the intestine and the liver (Rajala, M. et al. J. Clin. Invest. Vol. 111, 225-230 (2003)). Interestingly the molecular structure of RELMβ is highly homologous to that of the adipose-derived cytokine Resistin and RELMβ. These proteins share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X<sub>11</sub>-C-X<sub>8</sub>-C-X-C-X<sub>3</sub>-C-X<sub>10</sub>-C-X-C-X-C-X<sub>9</sub>-C-C. Recombinant Murine RELMβ is an 18.0 kDa, consisting of two 83 amino acid residue chains.
PROTQ9CPT4-2
Murine SF20 is a bone marrow stroma-derived growth factor. SF20 is expressed in bone marrow, spleen stroma cells, resting mononuclear cells, resting CD8+ and CD19+ cells and activated CD8+ T cells and has been shown to bind to the surface of cells expressing the receptor TSA-1 (Thymic shared Ag-1). Among its biological activities, SF20 stimulates the proliferation of FDCP2 cells (a mouse factor-dependent hemopoietic cell line) and mouse lymphoid cells. Recombinant murine SF20 is a 15.8 kDa protein containing 143 amino acid residues.
PROTQ9EP95-2
RELMα belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELMα and RELMβ are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELMα and Resistin are secreted exclusively by adipocytes while RELMβ is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELMα re still unknown. Recombinant murine RELMα is a 10.0 kDa monomeric protein containing 88 amino acid residues.