HY-115574

RSV L-protein-IN-1

RSV L-protein-IN-1 (compound D) is a potent inhibitor of Respiratory syncytial virus (RSV) (EC50=0.021 μM). RSV L-protein-IN-1 inhibits Polymerase (IC50=0.089 μM)，and blocks RSV mRNA synthesis by inhibiting guanylation of viral transcripts. RSV L-protein-IN-1 shows moderate cytotoxicity (CC50=8.4 μM，HEp-2)，also exhibits activity and lowers virus titers in mouse models of RSV infection[1].

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HY-155583

RNase L-IN-1

RNase L-IN-1 (compound 17a) is an inhibitor of RNase L, or Ribonuclease L. RNase L degrades RNAs to prevent viral replication, and mediates the innate immune responses and inflammation[1].

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HY-152204

Cathepsin L/S-IN-1

Cathepsin L/S-IN-1 is a dual inhibitor of Cathepsin L and Cathepsin S with IC50s of 4.10 μM and 1.79 μM, respectively. Cathepsin L/S-IN-1 shows a significant antimetastatic and invasive effects on pancreatic cancer BxPC-3 and PANC-1 cells[1].

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ABC-TC0704

MS-1-L

Human lung small cell carcinoma from pleural effusion. Lung cancer, small cell carcinoma. Cells are producing PTHrP.

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ABC-TC1233

THP 1 l

Species: human; Tissue: peripheral blood; Tumor: leukemia, acute monocytic; Derived from: THP-1.

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B600

1 L Flask

321.69 €