RecombinantHB-EGF,Human
406.5 EUR
406.5 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 965 - BK0073
Produktkategori: Företag och industri > Vetenskap och laboratorium
Leverantör:
Gentaur
Storlek: 10μg
Parameters
| Additional information | Proheparin-binding EGF-like growth factor (HB-EGF), also known as DTR, DTS and HEGFL, is a member of the EGF family of mitogens. It is expressed in macrophages, monocytes, endothelial cells and muscle cells. HB-EGF signals through the EGF receptor to stimulate the proliferation of smooth muscle cells, epithelial cells and keratinocytes. Compared to EGF, HB-EGF binds to the EGF receptor with a higher affinity and has been shown to bemore mitogenic, likely due to its ability to bind to heparin and heparin sulfate proteoglycans. HB-EGF has also been reported to act as a diphtheria toxin receptor, mediating endocytosis of the bound toxin. Heparin-binding EGF-like growth factor has been shown to interact with NRD1, Zinc finger and BTB domain-containing protein 16 and BAG1.Recombinant Human HB-EGF produced in E.coli cells is a polypeptide chain containing 86 amino acids. A fully biologically active molecule, rhHB-EGF has a molecular mass of 14 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript. |
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BK0073
RecombinantHB-EGF,Human
ED50 < 0.75ng/ml, measured in a cell proliferation assay using 3T3 cells.
406.5 €
BK0073
RecombinantHB-EGF,Human
ED50 < 0.75ng/ml, measured in a cell proliferation assay using 3T3 cells.
132 €
BK0218
RecombinantHB-EGF,Human
ED50 <0.5 ng/ml, measured in a cell proliferation assay using 3T3 cells.
4110 €
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