Catalog number: 426 - E40PO122
Product Category: Business & Industrial > Science & Laboratory
Size: 20ug
B1R-H52H6
Vaccinia Virus B18R, His Tag (B1R-H52H6) is expressed from human 293 cells (HEK293). It contains AA His 20 - Glu 351 (Accession # P25213).
92-624
B18R, also known as B19R in the Copenhagen strain of Vaccinia, is a type I interferon (IFN)-binding protein encoded by the B18R open reading frame in the Western Reserve strain of vaccinia virus. B18R exists in two forms, soluble and membrane-bound form and also has a broad species specificity. B18R has high affinity for human IFN-alpha and also binds rabbit, bovine, rat, pig, and mouse IFN-alpha and IFN-beta. Secreted B18R binds to uninfected and infected cells. B18R presents at the cell surface and protects cells from the antiviral state. It has shown that binding of soluble recombinant B18R protects cultured cells from IFN and allows vaccinia virus replication.
PKSQ050089-10ug
Vaccinia virus