Recombinant Rat FGF-21 protein
422.58 €
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Catalog number: 772 - CD00126-5ug
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 5ug
CD00126-5ug
Recombinant Rat FGF-21 protein
Fibroblast growth factor 21 (FGF-21) encoded by the FGF-21 gene belongs to the large FGF family and it is specifically induced by HMGCS2 activity. In mice, brown adipose tissue becomes a source of systemic FGF-21 after cold exposure. FGF-21 stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression) and the activity depends on the presence of KLB. Recombinant rat FGF-21 contains 180 amino acids residues and show limited binding to heparin. In addition, rat FGF-21 respectively shows 81 % and 92 % a.a. identity to human and Mouse FGF-21, and it show activity on Mouse and human cells.
422.58 €