Recombinant Mouse FER (N-GST tag)
671 €
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Catalog number: 10021 - Z600012
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 10 µg
Z600012
Recombinant Mouse FER (N-GST tag)
FER is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. FER plays a role in regulating cytoskeletal rearrangements and inside out signalling that accompany receptor ligand, cell matrix and cell cell interactions . Genetic analysis using transgenic mouse models implicate FER in the regulation of inflammation and innate immunity. Fer-deficient mice displayed enhanced recruitment of leukocytes in response to local LPS challenge. FER is required for cell-cycle progression in malignant cells. Decreasing the level of FER using RNAi impeded the proliferation of prostate and breast carcinoma cells and led to their arrest at the G0/G1 phase .
671 €