Recombinant Mouse EPHB1 (N-GST tag)
671 €
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Catalog number: 10021 - Z600011
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 10 µg
Z600011
Recombinant Mouse EPHB1 (N-GST tag)
EPHB1 is a member of the Eph family of receptor tyrosine kinases. Ligand-activated EPHB1 forms a signaling complex with Nck, paxillin, and focal adhesion kinase and induces tyrosine phosphorylation of paxillin in a c-Src-dependent manner to promote cell migration . In addition, activated EPHB1 recruits the adaptor proteins Grb2 and p52Shc and promotes p52Shc and c-Src tyrosine phosphorylation as well as MAPK/extracellular signal-regulated kinase (ERK) activation. Expression of dominant-negative c-Src significantly reduced EPHB1-dependent ERK1/2 activation and chemotaxis .
671 €
Z600029
Recombinant Mouse WNK4 (N-GST tag)
WNK4 or WNK lysine deficient protein kinase 4 is a member of the WNK family of serine-threonine protein kinases which is part of the tight junction complex in kidney cells. WNK4 can regulate the balance between NaCl reabsorption and K(+) secretion. WNK4 negatively regulates the surface expression of SLC12A3, and the loss of this regulation may cause an inherited form of hypertension . WNK4 regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. WNK4 is a positive regulator for the WNK-OSR1/SPAK-NCC cascade and is a potential target of antihypertensive drugs .
671 €
EPHB1-12492H
Recombinant Human EPHB1, GST-tagged
The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.