Recombinant Human TGFBR1 (ALK5) (N-GST tag)
924.5 €
924.5 €
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product details
Catalog number: 544 - MBS4160384-001mg
Product Category: Business & Industrial > Science & Laboratory
Supplier:
Gentaur
Size: 0.01mg
Z500385
Recombinant Human TGFBR1 (ALK5) (N-GST tag)
TGFßR1 or transforming growth factor, beta-receptor 1 is a member of the TGFß receptor subfamily and is a ser/thr protein kinase that forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. Mutations in TGFßR1gene have been associated with Marfan syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors . TGFßR1-dependent signaling is required for angiogenesis but not for the development of hematopoietic progenitor cells and functional hematopoiesis .
671 €