Catalog number: 544 - MBS4160265-5x001mg
Product Category: Business & Industrial > Science & Laboratory
Size: 5x0.01mg
Z500266
p70S6K is responsible for the phosphorylation of 40S ribosomal protein S6 and is ubiquitously expressed in human adult tissues . p70S6K is activated by serum stimulation and this activation is inhibited by wortmannin and rapamycin. p70S6k activity undergoes changes in the cell cycle and increases 20-fold in G1 cells released from G0 . p70S6K activation requires sequential phosphorylations at proline-directed residues in the putative autoinhibitory pseudosubstrate domain, as well as threonine 389 a site phosphorylated by phosphoinositide-dependent kinase 1 (PDK-1).
SPC-1040D-DY405
A polyclonal antibody for p70S6K (pThr412) from Human. The antibody is produced in rabbit after immunization with Human A phospho-specific peptide corresponding to residues surrounding Thr412 of human p70S6K (AA409-415). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This p70S6K (pThr412) antibody is conjugated to Dylight 405.
SPC-1040D-DY488
A polyclonal antibody for p70S6K (pThr412) from Human. The antibody is produced in rabbit after immunization with Human A phospho-specific peptide corresponding to residues surrounding Thr412 of human p70S6K (AA409-415). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This p70S6K (pThr412) antibody is conjugated to Dylight 488.
SPC-1040D-DY594
A polyclonal antibody for p70S6K (pThr412) from Human. The antibody is produced in rabbit after immunization with Human A phospho-specific peptide corresponding to residues surrounding Thr412 of human p70S6K (AA409-415). The Antibody is tested and validated for WB, AM assays with the following recommended dilutions: WB (1:250). This p70S6K (pThr412) antibody is conjugated to Dylight 594.