Recombinant Human IL-4RA/IL-4 R alpha Protein
357.24 €
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product details
Catalog number: 806 - RP00768
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 10μg
96-796
IL-4 R alpha Recombinant Protein
IL-4 is a pleiotropic cytokine produced by activated Th2 cells and mast cells, and plays a pivotal role in immune responses. The effects of IL-4 are mediated after binding to high affinity receptor complexes present on hematopoietic as well as non-hematopoietic cells. Hematopoietic cellular responses to IL-4 are mediated by a high affinity receptor complex comprised of the 140 kDa IL4Ralpha (CD124)subunit and the 70 kDa common cytokine γc chain (CD132).Interleukin 4 Receptor (IL4R) also known as CD124, IL4Ralpha and BSF receptor, is a type I cytokine receptor produced by activated Th2 cells and mast cells, and plays an important role in Th2-biased immune responses, alternative macrophage activation, mucosal immunity, allergic inflammation, tumor progression, and atherogenesis. A soluble form of the encoded IL4R protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. IL4R can alternatively associate with IL13Ra1 to form the type II receptor which is responsive to both IL4 and IL13. Interleukin-4 receptor has been shown to interact with SHC1.
1201.45 €
ILR-H5221
Human IL-4 R alpha / CD124 Protein, His Tag (MALS verified)
Human IL-4 R alpha, His Tag (ILR-H5221) is expressed from human 293 cells (HEK293). It contains AA Met 26 - His 232 (Accession # NP_000409.1).
593.40 €
ILR-H5221-1mg
Human IL-4 R alpha / CD124 Protein, His Tag (MALS verified)
Human IL-4 R alpha, His Tag (ILR-H5221) is expressed from human 293 cells (HEK293). It contains AA Met 26 - His 232 (Accession # NP_000409.1).
2843.16 €
ILR-H5221-50ug
Human IL-4 R alpha / CD124 Protein, His Tag (MALS verified)
Human IL-4 R alpha, His Tag (ILR-H5221) is expressed from human 293 cells (HEK293). It contains AA Met 26 - His 232 (Accession # NP_000409.1).