CSI068Ca01

Primary Canine Tracheal Smooth Muscle Cells (TSMC)

1750.33 €

CSI068Ra01

Primary Rat Tracheal Smooth Muscle Cells (TSMC)

1659.43 €

CSI068Rb01

Primary Rabbit Tracheal Smooth Muscle Cells (TSMC)

1780.63 €

ABC-TC3626

Human Gastric Smooth Muscle Cells

Smooth muscle is responsible for the contractility of hollow organs, such as blood vessels, the gastrointestinal tract, the bladder, and the uterus. Its structure differs greatly from that of skeletal muscle. The human stomach contains three layers of muscle in its walls, the outer longitudinal, the middle circular and the inner oblique and visceral smooth muscle cells makes up all three layers along the entire organ. Smooth muscle contraction is critical to peristalsis in the human stomach and the contraction may be mediated by activation of phospholipase through two distinct mechanisms (increased intracellular Ca2+ and G protein activation) and activating PKCepsilon-dependent mechanisms. In vitro study also shows that gastric smooth muscle cells express ET and eNOS and both calcium and sodium may be involved as current carriers in the generation of the plateau potential.HGSMC from Gentaur Research Laboratories are isolated from the human stomach. HGSMC are cryopreserved at secondary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HGSMC are characterized by immunofluorescent method with antibodies to andALPHA;-smooth muscle actin and desmin. HGSMC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HGSMC are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

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ABC-TC3657

Human Intestinal Smooth Muscle Cells

Smooth muscle contraction is the fundamental event in gastrointestinal motion. Although many of the biochemical mechanisms underlying the excitation-contraction coupling are not yet defined, it is known that cytosolic Ca2+ is the essential component in the coupling phenomenon. Inflammation of the human intestine causes thickening of the smooth muscle layers which results from the increases in the smooth muscle-specific actins. The increased smooth muscle actins may affect force production and further demonstrate the plasticity of smooth muscle in the inflamed intestine. Studies also show that human intestinal smooth muscle cells respond to IL-1beta and TNF-alpha stimulation by releasing IL-6, which might significantly contribute to the overall systemic inflammatory response. The availability of human intestinal smooth muscle cells in culture will considerably enhance our ability to study the contractile, proliferative and connective tissue responses of the smooth muscle of the human gastrointestinal tract.HISMC from Gentaur Research Laboratories are isolated from human intestine. HISMC are cryopreserved at passage one culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HISMC are characterized by immunofluorescent method with antibodies to andALPHA;-smooth muscle actin and desmin. HISMC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HISMC are guaranteed to further expand for 15 population doublings in the condition provided by Gentaur Research Laboratories.

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ABC-TC3686

Human Lung Smooth Muscle Cells

Human Lung Smooth Muscle Cells, when grown in LIVas SMC Medium, provide an ideal culture model for the study of angiogenesis, atherosclerosis, diabetes or vascular/pulmonary biology.Cell Features:HSMC are cryopreserved as secondary cells, e.g. cells are isolated from the stated tissue and expanded in culture vessels twice before cryopreservation.HAoSMC are isolated from human aorta (ascending and/or descending).HPASMC are isolated from human pulmonary artery.HCASMC are isolated from human coronary arteries.HLMSC are isolated from the lobes of the lungs.HBTSMC are isolated from the trachea and primary bronchi.HSMC can be grown without phenol red or antimicrobials when cultured in VascuLife SMC Medium.HSMC are extensively tested to meet quality standards and exhibit optimal performance.Gentaur guarantees performance and quality.

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