Pomalidomide-C4-NH2 hydrochloride
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Catalog number: 544 - MBS5800075-INQUIRE
Product Category: Business & Industrial > Science & Laboratory
Supplier:
Gentaur
Size: INQUIRE
HY-138845A
Pomalidomide-C4-NH2 (hydrochloride)
Pomalidomide-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].
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HY-115446A
Lenalidomide-C4-NH2 (hydrochloride)
Lenalidomide-C4-NH2 hydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C4-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC (Compound 24), which has IC50s of 0.98 nM and 13.7 nM in inhibition of RS4;11 and MOLM-13 acute leukemia cell lines growth, respectively[1].
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