PIM-1 Inhibitor 2
320.17 €
320.17 €
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Catalog number: 607 - A4519-5
Product Category: Business & Industrial > Science & Laboratory
Supplier:
Gentaur
Size: 5 mg
HY-157404
Pim-1/2 kinase inhibitor 2
Pim-1/2 kinase inhibitor 2 (compound 5b) is a competitive PIM-1 and PIM-2 kinase inhibitor with IC50s of 1.31 μM and 0.67 μM, respectively. Pim-1/2 kinase inhibitor 2 shows in-vitro low cytotoxicity against normal human lung fibroblast Wi-38 cell line and potent in-vitro anticancer activity against myeloid leukaemia (NFS-60), liver (HepG-2), prostate (PC-3), and colon (Caco-2) cancer cell lines[1].
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Chromatin/Epigenetics|Pim#JAK/STAT Signaling|Pim