RF16003-002mg

PD1 Antibody [7H6]

Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD-1-null mice who exhibit hyperactivated immune systems and autoimmune diseases. PD-1 is thus one of a growing number of immune checkpoint proteins.

479.30 €

RF16003-01mg

PD1 Antibody [7H6]

Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD-1-null mice who exhibit hyperactivated immune systems and autoimmune diseases. PD-1 is thus one of a growing number of immune checkpoint proteins.

1031.60 €

APG01821G

Monoclonal ALOX15 / 15-Lipoxygenase Antibody (clone 7H6), Clone: 7H6

A Monoclonal antibody against Human ALOX15 / 15-Lipoxygenase (clone 7H6). The antibodies are raised in Mouse and are from clone 7H6. This antibody is applicable in WB and IHC-P, IF, Flo

1097.06 €

MBS8539808-01mLAF635

Phospho-SMAD3 (S425) Mouse mAb (7H6)

914.43 €

AM06360SU-N

TrkC (NTRK3) mouse monoclonal antibody, clone 7H6, Ascites

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E45M17337

Lipin 1 (LPIN1) Mouse Monoclonal Antibody [Clone:7H6]

1052.92 €