OLIG2 Antibody
915.55 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 223 - 7743-01mg
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 0.1 mg
Parameters
| Additional information | Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
|---|---|
| Storage and shipping | OLIG2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
7743-002mg
OLIG2 Antibody
The oligodendrocyte transcription factors 1 and 2 (OLIG1 and OLIG2, respectively) make up part of basic helix-loop-helix (bHLH) family of transcription factors that are specifically expressed in zones of the neuroepithelium from which oligodendrocyte precursors emerge (1). Both OLIG1 and OLIG2 genes are downstream targets of Sonic hedgehog and are expressed exclusively in the central nervous system (2). OLIG2 is first observed in the ventral most p3 progenitor domain of the ventral neural tube while OLIG1 is first expressed in the dorsal portion of the p3 domain (2). Mice overexpressing OLIG2 exhibit impaired potassium channel expression in neural progenitors and proliferation of these cells similar to that seen in Down Syndrome, suggesting that OLIG2 may play a role in this pathology (3).
439.27 €
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