Catalog number: 544 - MBS669106-1Vial
Product Category: Business & Industrial > Science & Laboratory
Size: 1Vial
RC1027
The TLR2/NF-kB Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses full-length human Toll-like receptor 2 (TLR2) and Renilla luciferase reporter gene under the transcriptional control of the NF-kB response element. TLR2 is one of the key innate immune receptors. Functional activity of the cell line has been validated by TLR2 ligand assay, in which upon activation by Pam3CSK4, TLR2 quickly initiates downstream signaling pathway and mediates nuclear translocation of NF-kB (Figure 1).
RC1028
The TLR3/NF-kB Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses full-length human Toll-like receptor 3 (TLR3) and Renilla luciferase reporter gene under the transcriptional control of the NF-kB response element. Functional activity of the cell line has been validated by TLR3 ligand assay, in which upon activation by poly (I:C), TLR3 quickly initiates TRIF-dependent signaling pathway and mediates nuclear translocation of NF-kB (Figure 1).
RC1029
The TLR7/NF-kB Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses full-length human Toll-like receptor 7 (TLR7) and Renilla luciferase reporter gene under the transcriptional control of the NF-kB response element. TLR7 is one of the key innate immune receptors. Functional activity of the cell line has been validated by TLR7 ligand assay, in which upon activation by R848, TLR7 quickly initiates downstream signaling pathway and mediates nuclear translocation of NF-kB (Figure 1).