Catalog number: 808 - TFE-7108
Product Category: Business & Industrial > Science & Laboratory
Size: 1Kit
OKAG00321
Description of target: This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.;Species reactivity: Human, Mouse, Rat;Application: ELISA;Assay info: Assay Type: Qualitative DNA Binding ELISA ;Sensitivity:
TFE-7108
NF-κB p100/p52 (Phospho-Ser865) TFact™ Colorimetric DNA-Binding ELISA Kit
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FKHRL1 (Phospho-Ser253) TFact™ Colorimetric DNA-Binding ELISA Kit