Myc (Phospho-Thr58) DNA-Binding ELISA Kit (OKAG00319)
1598.43 €
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Catalog number: 247 - OKAG00319
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 96 Wells
OKAG00319
Myc (Phospho-Thr58) DNA-Binding ELISA Kit (OKAG00319)
Description of target: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.;Species reactivity: Human, Mouse, Rat;Application: ELISA;Assay info: Assay Type: Qualitative DNA Binding ELISA ;Sensitivity:
1598.43 €
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