Mouse Serum Anti-OVA IgE Antibody Assay Kit

3004

Mouse Anti-OVA IgE Antibody Assay Kit

Serum, Plasma, Culture Media

815 €

MBS1607603-10x96StripWells

Mouse OVA-Specific Serum IgE ELISA Kit

5227.62 €

MBS1607603-48StripWells

Mouse OVA-Specific Serum IgE ELISA Kit

573.88 €

EHM-V1

ELISA Assay Kit for Anti-HER-2 h-mAb in Mouse Serum

Human Epidermal growth factor Receptor 2 (HER2) is also called ERBB2, HER-2,HER-2 /neu, NEU, NGL,TKR1 and c-erb B2,and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2 is a cell membrane surface-bound receptor tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. HER2 is thought to be an orphan receptor, with none of the EGF family of ligands able to activate it. Approximately 30% of breast cancers have an amplification of the HER2 gene or overexpression of its protein product. Overexpression of this receptor in breast cancer is associated with increased disease recurrence and worse prognosis. HER2 appears to play roles in development, cancer, communication at the neuromuscular junction and regulation of cell growth and differentiation .

1692.12 €

KLX0295

Rabbit Anti-OVA-IgE, Anti-OVA-IgE GENLISA ELISA

686.5 €

ECM-V1

ELISA Assay Kit for Anti-CTLA-4 h-mAb in Mouse Serum

CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152 (Cluster of differentiation 152), is a protein receptor that downregulates the immune system. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. The protein contains an extracellular V domain, a transmembrane domain, and a cytoplasmic tail. Alternate splice variants, encoding different isoforms. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. Fusion proteins of CTLA4 and antibodies (CTLA4-Ig) have been used in clinical trials for rheumatoid arthritis.

619.56 €