Mouse Anti-Human CD86 Monoclonal Antibody, PE Conjugated Clone B-T7
598.93 €
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Catalog number: 544 - MBS335276-100Tests
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 100Tests
DL20256F-50Tests
Anti-Human CD86 Monoclonal Antibody(PerCP Conjugated)
CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.
969.60 €