A Monoclonal antibody against Human SELPLG / PSGL-1 / CD162 (clone HECA-452). The antibodies are raised in Rat and are from clone HECA-452. This antibody is applicable in IHC-P, Flo
YF-452 is a potent inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2). YF-452 remarkably inhibits the migration, invasion and tube-like structure formation of human umbilical vein endothelial cells (HUVECs) with little toxicity. YF-452 inhibits VEGF-induced phosphorylation of VEGFR2 kinase and the downstream protein kinases including extracellular signal regulated kinase (ERK), focal adhesion kinase (FAK) and Src. YF-452 is a potential antiangiogenic agent candidate for cancer research[1].
AB-452, a Dihydroquinolizinone (DHQ) analogue, is a potent and orally active HBV RNA destabilizer. AB-452 inhibits PAPD5/7 proteins in vitro with good in vivo efficacy in a chronic HBV mouse model[1].
A Monoclonal antibody against Human SELPLG / PSGL-1 / CD162 (clone HECA-452). The antibodies are raised in Rat and are from clone HECA-452. This antibody is applicable in IHC-P, Flo