PV-1019 (NSC 744039) is a potent, selective Chk2 inhibitor with an IC50 value of 24 nM. PV-1019 inhibits the Topotecan (HY-13768)-induced Chk2 autophosphorylation. PV-1019 inhibits IR-induced apoptosis[1].
A Monoclonal antibody against Human CD50 / ICAM-3. The antibodies are raised in Mouse and are from clone ICAM3/1019. This antibody is applicable in WB, IHC and IF, FC