LE135
0.01 EURAsk for quotation
On request
quantity
Produktdetaljer
Katalognummer: 931 - T22920-1g
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 1g
Parameters
| Additional information | SMILES: O=C(O)C=1C=CC(=CC1)C2=NC=3C=C4C(=CC3N(C=5C=CC=CC25)C)C(C)(C)CCC4(C)C; Formula: C29H30N2O2 |
|---|
HY-107436
LE135
LE135 is a potent RAR antagonist that binds selectively to RARα (Ki of 1.4 μM) and RARβ (Ki of 220 nM), and has a higher affinity to RARβ. LE135 is highly selective over RARγ, RXRα, RXRβ and RXRγ. LE135 is also a potent TRPV1 and TRPA1 receptors activator with EC50s of 2.5 μM and 20 μM, respectively[1][2].
214.35 €
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