ISRE Leeporter Luciferase Reporter-RAW264.7 Cell Line
11308.25 €
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Catalog number: 544 - MBS669105-5x1Vial
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 5x1Vial
RC1034
CRE Luciferase Reporter-HEK293 Cell Line
The CRE Luciferase <a href="https://www.bosterbio.com/cells/reporter-cell-lines" style="color:#ea8d28">Reporter cell line</a> is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the cAMP response element (CRE). The CRE cell line is designed to monitor the cAMP/PKA signaling pathways and can be used for studying GPCR-linked cAMP/PKA signaling pathways as well as screening of agonists, antagonists or signaling inhibitors related with the cAMP/PKA signaling pathways. Functional activity of the cell line has been validated by serum stimulation assay (Figure 1).
4308.00 €
RC1036
SBE Luciferase Reporter-HEK293 Cell Line
The SBE Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the smad binding element (SBE). SMADs are intracellular signaling mediators that transduce extracellular signals from transforming growth factor beta (TGF-beta) ligands to the nucleus where they activate downstream gene transcription. The TGF-beta signaling pathway is involved in many cellular processes in both the adult organism and the developing embryo including cell growth, cell differentiation, apoptosis, cellular homeostasis and other cellular functions. The SBE induction by TGF-beta is shown in Figure 1.
2947.20 €
RC1037
MRE Luciferase Reporter HEK293 Cell Line
The MRE Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the metal response element (MRE). MRE is targeted by MRE-binding transcription factor-1 (MTF-1) which is a zinc finger transcription factor and plays a major role in induction of metallothionein gene expression in response to cellular stress caused by heavy metals such as zinc and cadmium. The MRE induction by ZnSO4 is shown in Figure 1.