ABC-TC5517

Human Thymic Epithelial Cells

Thymic epithelial cells (TyEpiC) are vital regulators of thymocyte development and T lymphocyte (T-cell) tolerance. The thymus contains two types of TyEpiC, cortical and medullary thymic epithelial cells, which regulate the positive selection of thymocytes and the negative selection of autoreactive T-cells. The inability of TyEpiC to remove autoreactive T-cells in the thymus can affect self-tolerance and contribute to the development of autoimmune diseases such as myasthenia gravis, type 1 diabetes, rheumatoid arthritis, and multiple sclerosis [3]. Studies have shown that changes in the expression of tumor necrosis factor receptor family members and transcription factors Foxn1 and autoimmune regulator (Aire) can alter the thymic microenvironment and self-tolerance. Human TyEpiC are an excellent in vitro model to study the mechanisms that modulate TyEpiC functionality and to develop targeted treatments for autoimmune disorders.

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CSC-I1919Z

Immortalized Human Thymic Epithelial Cells

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T4980

Human Primary Thymic Epithelial Cells

1594.29 €

ABC-TC3691

Human Mammary Epithelial Cells, Adult

The mammary gland consists of pseudostratified epithelia, with myoepithelila cells resting upon a basement membrane and apical glandular epithelial cells facing the lumen of the ducts and alveoli. Mammary epithelial cells undergo changes in growth, invasion, and differentiation throughout much of adulthood, and most strikingly during pregnancy, lactation, and involution. They proliferate and invade the surrounding extracellular matrix during the fetal and postnatal development of the gland, and then more vigorously at puberty as the branches of the mammary epithelial tree are formed.HMEpiC from Gentaur Research Laboratories are isolated from normal human breast tissue. HMEpiC are cryopreserved at passage one culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HMEpiC are characterized by immunofluorescent method with cytokeratine antibodies. HMEpiC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HMEpiC are guaranteed to further expand for 15 population doublings in the conditions provided by Gentaur Research Laboratories

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ABC-TC3692

Human Mammary Epithelial Cells, Female

Human Mammary Epithelial Cells, when grown in LIMam Medium, provide an ideal serum-free culture model for many areas of research. Common uses of HMEC include the stages of breast cancer development, three dimensional culture and carcinogen screening.Cell Features:HMEC are cryopreserved as tertiary cells, e.g. cells are isolated from human mammary tissue and expanded three times in culture vessels before being harvested for cryopreservation.HMEC are extensively tested for quality and optimal performance.Gentaur guarantees performance and quality.

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ABC-TC3693

Human Mammary Epithelial Cells, Male

Human Mammary Epithelial Cells, when grown in LIMam Medium, provide an ideal serum-free culture model for many areas of research. Common uses of HMEC include the study of breast cancer development, three dimensional culture and carcinogen screening.Cell Features:HMEC are cryopreserved as tertiary cells, e.g. cells are isolated from human mammary tissue and expanded three times in culture vessels before being harvested for cryopreservation.HMEC are extensively tested for quality and optimal performance.Gentaur guarantees performance and quality.

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