IL-11 Antibody
365.25 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 808 - R12-2199-50ul
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 50μl
Parameters
| Storage and shipping | 4c - 20c |
|---|
8453-002mg
IL-11 Antibody
Interleukin 11 is a pleiotropic cytokine that has multiple effects on both hematopoietic and nonhematopoietic cells. Many of the biological effects described for IL-11 overlap those for IL-6 (1). It directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (2). IL-11 promotes the proliferation of hepatocytes in response to liver damage. IL-11 binds to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 (3). Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelo-suppressive chemotherapy (4).
439.27 €
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