IGF1 Chemi-Luminescent ELISA Kit (Mouse) (OKCD03605)
2005.60 €
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Catalog number: 247 - OKCD03605
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 96 Wells
OKCD03605
IGF1 Chemi-Luminescent ELISA Kit (Mouse) (OKCD03605)
Description of target: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.0274 ng/mL
2005.60 €
OKCD03277
ACE Chemi-Luminescent ELISA Kit (Mouse) (OKCD03277)
Description of target: Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. This GPIase activity seems to be crucial for the egg-binding ability of the sperm.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 54.9 pg/mL
2005.60 €
OKCD03607
IGF2 Chemi-Luminescent ELISA Kit (Mouse) (OKCD03607)
Description of target: The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development. Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.37 pg/mL
2005.60 €
OKCD03615
IL10 Chemi-Luminescent ELISA Kit (Mouse) (OKCD03615)
Description of target: Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.37 pg/mL
2005.60 €
OKCD03616
IL11 Chemi-Luminescent ELISA Kit (Mouse) (OKCD03616)
Description of target: Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production . Also promotes the proliferation of hepatocytes in response to liver damage . Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation, also in the context of various cancers . Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3 .;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.37 pg/mL